Saturday, November 26, 2011

The early stages of Alzheimer's disease associated with reduced body mass index

The early stages of Alzheimer's disease associated with reduced body mass index
Study suggests that people in the early stages of Alzheimer's disease have a body mass index have a low.



 
Scientists from the University of Kansas, said the results indicate that the changes that occur in the early stages of Alzheimer's disease may be linked in the brain and lead to a change in metabolism in the body caused by the disease leads to reduced body mass index.


The researchers studied the changes that occur early in the brain that are associated with Alzheimer's disease using advanced technology for brain imaging study included 506 people. As Achtbarainat of cerebrospinal fluid for two types of biomarkers that can be present before the first symptoms of Alzheimer's disease.


The study included participants do not have memory problems, and people with mild cognitive impairment and people suffering from Alzheimer's disease. Found that people who suffer from mild cognitive impairment have memory problems are mild, but not to the extent that it interferes with their daily lives.


The study found that people who were biomarkers for Alzheimer clear and few signs of memory amyloid in their brains had their body mass index less than 25.



  
Found that among those with mild weakness in cognition, it was 85 per cent of them had a body mass index less than 25 and have signs of beta amyloid in their brains, compared with 48 per cent of people who suffer from mild cognitive impairment was a high weight.


Previous studies have shown that weight gain in middle age can actually increase the risk of developing Alzheimer's disease, but those who are overweight later in life may be less susceptible to the disease, known as the "obesity paradox."


However, scientists did not recommend reducing the weight to reduce the risk of infection. However, low body mass index may be a result of the disease, not the cause of it.


Dr Anne Corbett, director of research at the Alzheimer's Association: "Until now it was unclear whether the lower body mass index is in fact part of the Alzheimer's disease, or side effects caused by this disease.



 
She added, "Although this study shows a link between Alzheimer's disease and the changes that occur in the brain, there was no association between BMI and symptoms such as loss of memory.


"There is a need for more work before to say whether these results can be used to develop better ways to diagnose the early stages of the disease.


"What we do know is that living well will reduce the risk of Alzheimer's disease. Alzheimer's Association recommends that people eat healthy food and doing regular exercise."

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