Wednesday, November 30, 2011

Defective gene is the risk of multiple myeloma cancer

Defective gene is the risk of multiple myeloma cancer
The scientists in the United Kingdom for the first time according to the research that the genetic differences and gene defects may increase the risk of cancer, multiple myeloma, or cancer of plasma cells (myeloma).



 
He said scientists from the Institute of Cancer Research (ICR) that people who carry these genes have a higher risk by 30 per cent of the cancer myeloid myeloma.
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The multiple myeloma is a cancer of plasma cells of aggression, a type of white blood cells in bone marrow.


And is diagnosed nearly 4000 people in the UK each year, on average patient stays of three to five years survival after diagnosis, and this despite receiving intensive treatment.



 
Already known that relatives of patients with multiple myeloma have Mkhatrmen 2-4 times the progression of the disease they have, but scientists have been unable to identify the genes responsible.



 
The many associations using a technique called total study genetic makeup, checked out the scientists DNA 1.675 for patients suffering from multiple myeloma and this compared to examine the DNA for 5.900 people is true does not suffer from anything.



 
Were found in two regions of DNA with genetic differences, which were more common in people who suffer from multiple myeloma, and so was associated with an increased risk of disease.



 
Scientists said that there are genes common among the general population, are estimated to play a role in 37 per cent of all cases of myeloma in the European countries.



 
Said Albroovissourgaret Morgan of the ICR and Royal Marsden Ormond: "Multiple myeloma is a cancer, an aggressive because, unfortunately, rates of survival are few. More learning about the biology of Alttorlmred multiple myeloma, we hope to find a new drug to achieve the target, which can improve the situation of patients.



 
"Multiple myeloma is more common in the elderly, and this is most important to find new treatments."

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